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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK2
All Species:
0.91
Human Site:
T723
Identified Species:
2.22
UniProt:
Q8IWQ3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWQ3
NP_003948.2
736
81633
T723
E
Y
P
T
G
K
D
T
A
K
M
G
P
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850919
676
75195
A663
E
R
P
T
A
Q
D
A
A
R
T
G
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z98
735
81715
M722
E
Y
P
M
G
K
D
M
A
K
M
G
P
P
A
Rat
Rattus norvegicus
Q8VHF0
797
88733
F774
L
S
L
N
G
V
R
F
K
R
I
S
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA88
798
88848
P769
Q
S
F
S
A
Q
S
P
S
Y
D
A
V
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S1114
V
E
P
M
S
G
M
S
L
L
A
G
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
E839
R
S
N
S
E
T
A
E
H
E
R
N
R
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
H1036
S
K
L
T
R
R
D
H
N
R
E
S
M
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
D500
G
P
Q
F
L
F
L
D
L
C
A
A
F
L
T
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
N1322
E
E
H
T
K
L
D
N
K
I
S
E
E
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
89.8
N.A.
97.9
25.4
N.A.
N.A.
27.4
N.A.
25.1
N.A.
50.9
N.A.
23.1
N.A.
Protein Similarity:
100
N.A.
N.A.
90.3
N.A.
98.7
43.2
N.A.
N.A.
43.9
N.A.
37.9
N.A.
63.5
N.A.
37.3
N.A.
P-Site Identity:
100
N.A.
N.A.
53.3
N.A.
80
6.6
N.A.
N.A.
0
N.A.
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
80
26.6
N.A.
N.A.
26.6
N.A.
20
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
10
10
30
0
20
20
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
10
0
0
10
0
0
0
0
% D
% Glu:
40
20
0
0
10
0
0
10
0
10
10
10
10
10
0
% E
% Phe:
0
0
10
10
0
10
0
10
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
30
10
0
0
0
0
0
40
10
0
0
% G
% His:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
10
0
0
10
20
0
0
20
20
0
0
10
0
0
% K
% Leu:
10
0
20
0
10
10
10
0
20
10
0
0
0
10
30
% L
% Met:
0
0
0
20
0
0
10
10
0
0
20
0
10
0
0
% M
% Asn:
0
0
10
10
0
0
0
10
10
0
0
10
0
0
0
% N
% Pro:
0
10
40
0
0
0
0
10
0
0
0
0
30
30
0
% P
% Gln:
10
0
10
0
0
20
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
10
0
0
10
10
10
0
0
30
10
0
10
0
0
% R
% Ser:
10
30
0
20
10
0
10
10
10
0
10
20
0
10
20
% S
% Thr:
0
0
0
40
0
10
0
10
0
0
10
0
0
30
20
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _